Brand name: Faslodex
Active Ingeridents (Generic Name) : Fulvestrant
Company Name: Astrazeneca
Package: One prefilled syringe containing 5ml or 250mg Fulvenat (Fulvestrant)
Strength : 250mg/5ml
Fulvenat (Fulvestrant) is an anti-estrogen medication. It works by blocking the actions of estrogen in the body. Certain types of breast cancer use estrogen to grow and multiply in the body.
Fulvenat (Fulvestrant) is used to treat a certain type of hormone-related breast cancer in postmenopausal women, when the cancer has spread to other parts of the body after treatment with anti-estrogen medication.
Fulvenat (Fulvestrant) is also used together with a medicine called palbociclib, to treat certain hormone-related breast cancer that has progressed or spread after treatment with hormonal therapy.
Mechanism of action:
Fulvenat (Fulvestrant) competitively and reversibly binds to estrogen receptors present in cancer cells and achieves its anti-estrogen effects through two separate mechanisms. First, Fulvenat (Fulvestrant) binds to the receptors and downregulates them so that estrogen is no longer able to bind to these receptors. Second, Fulvenat (Fulvestrant) degrades the estrogen receptors to which it is bound. Both of these mechanisms inhibit the growth of tamoxifen-resistant as well as estrogen-sensitive human breast cancer cell lines.
Dosage & Administration:
As an injection into the muscle (intramuscular, IM), Fulvenat (Fulvestrant) is usually given as a once a month injection. Your doctor will determine any variations to this dosing or schedule.
Get emergency medical help if you have signs of an allergic reaction to Fulvenat (Fulvestrant): hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Common Fulvenat (Fulvestrant) side effects may include:
Headache, bone pain, joint pain, muscle pain, nausea, vomiting, loss of appetite, constipation; weakness, feeling tired; cough, trouble breathing; abnormal liver function tests; hot flashes; or pain where the medicine was injected.
- Before starting Fulvenat (Fulvestrant) treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.). Do not take aspirin, or products containing aspirin unless your doctor specifically permits this.
- Let your health care professional know if you have ever had a blood clot that required medical treatment.
- Inform your health care professional if you are pregnant or may be pregnant prior to starting this treatment. Pregnancy category D (Fulvenat (Fulvestrant) may be hazardous to the fetus. Women who are pregnant or become pregnant must be advised of the potential hazard to the fetus).
Store: Fulvenat (Fulvestrant) is handled and stored by a health care provider. Keep all medicines out of the reach of children and away from pets.
- As Per Order Requirement Per Day
- 1-12 Days
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